Low-level resistance to fluoroquinolones among Salmonella and Shigella
نویسندگان
چکیده
منابع مشابه
Antibiotic resistance of Shigella and Salmonella bacteria in children with acute diarrhea
Background: Diarrhea with salmonella and shigella infections is one of the main causes of mortality in children less than 5 years. Determining the antibiotic resistance of these bacteria is one of the most important methods in the treatment of diarrhea. This study was performed to evaluate antibiotic resistance of Salmonella and Shigella pathogenic bacteria in children with acute diarrhea refer...
متن کاملEvaluation of Antibiotic Resistance to Fluoroquinolones and Third Generation Cephalosporines in Iranian Clinical Isolates of Salmonella spp.
Salmonella enterica serotypes are one of the most important food borne pathogens and significant public health concerns around the world in humans and other animal species. A total of eighty three epidemiologically unrelated clinical isolates of Salmonella enterica serovars were subjected to antimicrobial susceptibility testing. Eleven isolates (13.1%) which were resistant to at least 4 groups ...
متن کاملA Contribution of MdfA to Resistance to Fluoroquinolones in Shigella flexneri
In this study, we measured the drug resistance conferred by mdfA mutations in two Shigella flexneri strains. A mutant in mdfA genes was constructed by polymerase chain reaction-based, one-step inactivation of chromosomal genes. The antimicrobial susceptibility of parent and mutant strains to fluoroquinolones was determined by minimal inhibitory concentration (MICs). The △mdfA mutants were somew...
متن کاملClinical implications of reduced susceptibility to fluoroquinolones in paediatric Shigella sonnei and Shigella flexneri infections
OBJECTIVES We aimed to quantify the impact of fluoroquinolone resistance on the clinical outcome of paediatric shigellosis patients treated with fluoroquinolones in southern Vietnam. Such information is important to inform therapeutic management for infections caused by this increasingly drug-resistant pathogen, responsible for high morbidity and mortality in young children globally. METHODS ...
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The activities of six fluoroquinolones were determined for 117 separate strains of Shigella sonnei. The order of increasing activity (MICs for 90% of strains tested) was enoxacin (0.25 micrograms/ml), temafloxacin (0.032 micrograms/ml), sparfloxacin (0.016 micrograms/ml), CI-960 (0.008 micrograms/ml), ciprofloxacin (0.008 micrograms/ml), and PD-131628-2 (0.008 micrograms/ml). These data, along ...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2000
ISSN: 1198-743X
DOI: 10.1046/j.1469-0691.2000.00180.x